I was born with ADD and have struggled with depression and suicidality since 14. After heavy LSD use, I ended up in a five-year HPPD nightmare — stuck in cycles of depersonalization, psychosis, and voices. THC made me instantly paranoid and delusional, until I discovered D2 blockers like Amisulpride. They silenced the chaos — even thoughts I’d mistaken for just being “me.” SSRIs cured a deep chest pain I didn’t know wasn’t normal. That’s when I realized: I could trace my symptoms back to neurotransmitter pathways — and start mapping them out.
This article aims to show that ADHD in combination with chronic cannabis abuse does substantially increase the risk of developing schizophrenia and other disorders.
I'm not a neuro-biologist. This article doesn't mean to add any scientific value. Please do not cite anything or take its plausibility/correctness for granted. This is just a hobby and part of therapy in terms of fun activity.
Transcription is the first step in gene expression, where genetic information is transferred from DNA to RNA. This DNA-dependent process, catalyzed by RNA polymerase, produces various RNA species such as mRNA, tRNA, and rRNA. Transcription occurs in three phases-initiation, elongation, and termination-and is tightly regulated by proteins and DNA elements like promoters, enhancers, and silencers. Gene regulation determines which genes are active, how strongly they are transcribed, and responds to cellular and environmental signals. Disruptions in these mechanisms can lead to developmental disorders and diseases such as cancer.
This is a curated collection of neurobiology articles that I found particularly insightful and useful. Topics range from ADHD, addiction, and anxiety to psychosis, schizophrenia, and withdrawal. I put this list together for anyone interested in understanding how brain chemistry affects mental health. I’ll continue updating it as I come across more valuable research.
With over 24 million users, cannabis is the most widely used drug in the USA; a seemingly harmless substance if you smoke a joint in the morning - abuse, however should not be underestimated as it has many long term consequences.
This article contains a collection of basic neurobiological knowledge. If you are interested in this topic, feel free to read the following sections. However, do not expect any conclusions.
TypeScript is a strongly typed superset of JavaScript that compiles to plain JS. It improves code quality, catches errors early, and enhances developer productivity with powerful IDE support like autocompletion, type inference, and safe refactoring. It makes large codebases easier to manage, scales better, and is widely adopted in professional frontend and fullstack development. Mastering TypeScript is essential for advancing in modern development practices.
It’s your life - your responsibility.
- Depression
- Life’s a bitch.
- Depression often sticks with you forever.
- Learn to adapt and live with it.
- It’s the little things.
- Drugs will make it worse long-term.
[...]
I want to share anectdotal insights into how SSRIs might have cured my MDD after 20 years of suicidality.
I was born with ADD and barely made it through classes. I was good enough to pass without learning or doing home work, but as I grew up, Depression, addiction, chronic pain and psychosis became such a burden that I wanted to begin understanding what's wrong with me that no doctor can fix.
[...]
Git is a version control system that enables collaboration and code tracking. An important aspect is the use of branches to work on features and fixes. When working on a branch, two key commands are git merge
and git rebase
. The difference lies in how the history is handled. Merging preserves the history, while rebasing moves local commits on top of the latest remote changes, creating a linear history. Additionally, options like --no-ff
and --squash
affect how the commit history appears, with --no-ff
keeping individual commits and --squash
combining them into one.